Rita C Tostes Selected Research

Interleukin-10 (Interleukin 10)

2/2019	Interleukin-10 negatively modulates extracellular signal-regulated kinases 1 and 2 in aorta from hypertensive mouse induced by angiotensin II infusion.
9/2018	O-Glycosylation with O-linked β-N-acetylglucosamine increases vascular contraction: Possible modulatory role on Interleukin-10 signaling pathway.
1/2016	Interleukin-10 limits increased blood pressure and vascular RhoA/Rho-kinase signaling in angiotensin II-infused mice.
8/2013	P2X7 receptor activation contributes to an initial upstream mechanism of lipopolysaccharide-induced vascular dysfunction.

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Rita C Tostes Research Topics

Disease

59	Hypertension (High Blood Pressure) 04/2024 - 10/2003
26	Cardiovascular Diseases (Cardiovascular Disease) 05/2024 - 01/2008
19	Inflammation (Inflammations) 04/2024 - 10/2005
17	Obesity 01/2022 - 05/2008
8	Erectile Dysfunction 09/2017 - 12/2008
7	Hyperglycemia 12/2023 - 02/2009
7	Type 2 Diabetes Mellitus (MODY) 01/2020 - 11/2010
7	Insulin Resistance 01/2019 - 11/2010
6	COVID-19 12/2023 - 07/2021
6	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2021 - 07/2014
6	Body Weight (Weight, Body) 12/2018 - 02/2006
5	Vascular Remodeling 01/2021 - 06/2012
5	Stroke (Strokes) 08/2018 - 02/2009
4	Infections 12/2023 - 01/2022
4	Vascular System Injuries 01/2023 - 01/2015
4	Dysbiosis 01/2021 - 05/2018
4	Atherosclerosis 01/2021 - 03/2009
4	Metabolic Diseases (Metabolic Disease) 01/2021 - 01/2016
4	Diabetes Mellitus 01/2021 - 10/2015
4	Hypertrophy 01/2019 - 01/2014
3	Heart Failure 01/2021 - 04/2015
3	Fibrosis (Cirrhosis) 01/2021 - 07/2011
3	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2020 - 01/2017
2	Porcine Reproductive and Respiratory Syndrome (PRRS) 04/2024 - 01/2020
2	Sepsis (Septicemia) 12/2021 - 01/2019
2	Hypotension (Low Blood Pressure) 01/2020 - 01/2019
2	Dyslipidemias (Dyslipidemia) 01/2019 - 05/2017
2	Cardiomegaly (Heart Hypertrophy) 01/2019 - 01/2017
2	Vascular Diseases (Vascular Disease) 10/2018 - 01/2009
2	Weight Gain 05/2018 - 10/2015
2	Hyperaldosteronism (Conn Syndrome) 12/2016 - 07/2011
2	Albuminuria 01/2016 - 07/2011
2	Necrosis 08/2013 - 03/2009

Drug/Important Bio-Agent (IBA)

17	Proteins (Proteins, Gene)FDA Link 10/2023 - 10/2005
15	Reactive Oxygen Species (Oxygen Radicals)IBA 12/2023 - 10/2005
13	CytokinesIBA 04/2024 - 01/2009
11	SaltsIBA 05/2012 - 10/2003
9	AldosteroneIBA 04/2024 - 10/2005
7	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2023 - 01/2012
7	Vasoconstrictor AgentsIBA 10/2017 - 01/2008
7	Desoxycorticosterone Acetate (DOCA)FDA Link 05/2012 - 10/2003
6	AdipokinesIBA 04/2024 - 07/2014
6	Interleukin-6 (Interleukin 6)IBA 12/2023 - 10/2017
6	AcetylglucosamineIBA 12/2023 - 02/2009
6	Ethanol (Ethyl Alcohol)IBA 04/2023 - 03/2008
6	Testosterone (Sustanon)FDA Link 01/2023 - 01/2012
6	Angiotensin IIIBA 01/2021 - 02/2008
6	Glucose (Dextrose)FDA LinkGeneric 01/2019 - 11/2010
5	NADPH Oxidases (NAD(P)H oxidase)IBA 05/2024 - 02/2006
5	AntioxidantsIBA 01/2023 - 12/2015
5	MineralocorticoidsIBA 01/2019 - 04/2004
5	Endothelin-1 (Endothelin 1)IBA 09/2011 - 10/2003
5	Desoxycorticosterone (Deoxycorticosterone)IBA 02/2009 - 10/2003
5	Endothelins (Endothelin)IBA 02/2009 - 10/2003
4	InflammasomesIBA 01/2021 - 12/2016
4	Interleukin-10 (Interleukin 10)IBA 02/2019 - 08/2013
4	Insulin (Novolin)FDA Link 01/2019 - 01/2014
4	Acetates (Acetic Acid Esters)FDA Link 02/2009 - 10/2003
3	Pattern Recognition ReceptorsIBA 04/2024 - 01/2020
3	AngiotensinsIBA 04/2024 - 11/2004
3	Matrix Metalloproteinases (MMPs)IBA 10/2023 - 10/2017
3	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 01/2023 - 03/2010
3	rho-Associated KinasesIBA 01/2023 - 01/2016
3	Mitochondrial DNA (mtDNA)IBA 01/2022 - 01/2017
3	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 03/2019 - 04/2015
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2019 - 03/2009
3	Estrogens (Estrogen)FDA Link 01/2019 - 03/2013
3	Spironolactone (Aldactone)FDA LinkGeneric 01/2019 - 01/2015
3	AndrogensIBA 09/2017 - 01/2012
3	EnzymesIBA 01/2017 - 11/2011
3	LipidsIBA 01/2016 - 06/2013
2	ReninIBA 04/2024 - 01/2014
2	Matrix Metalloproteinase 2 (Gelatinase A)IBA 10/2023 - 10/2017
2	Doxycycline (Periostat)FDA LinkGeneric 10/2023 - 10/2017
2	Serotonin (5 Hydroxytryptamine)IBA 01/2023 - 01/2016
2	Oxidants (Oxidizing Agents)IBA 01/2023 - 01/2019
2	MelatoninIBA 10/2022 - 03/2021
2	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 12/2021 - 03/2012
2	CalciumIBA 10/2021 - 02/2009
2	Streptozocin (Streptozotocin)FDA Link 01/2020 - 10/2017
2	NLR ProteinsIBA 01/2020 - 01/2017
2	Atorvastatin (Lipitor)FDA Link 03/2019 - 04/2015
2	Acetylcholine (Acetylcholine Chloride)FDA Link 01/2019 - 10/2009
2	LipopolysaccharidesIBA 01/2019 - 01/2019
2	Messenger RNA (mRNA)IBA 01/2019 - 05/2017
2	CCX832IBA 12/2018 - 05/2017
2	Mineralocorticoid Receptors (Mineralocorticoid Receptor)IBA 10/2018 - 10/2015
2	ProstaglandinsIBA 01/2016 - 08/2015
2	Leptin ReceptorsIBA 01/2015 - 05/2008
2	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 01/2014 - 01/2010
2	Clopidogrel (Plavix)FDA Link 01/2014 - 04/2010
2	ArginaseIBA 03/2011 - 12/2010
2	CationsIBA 01/2011 - 12/2010
2	MagnesiumIBA 01/2011 - 12/2010
2	Phosphotransferases (Kinase)IBA 03/2010 - 10/2005

Therapy/Procedure

5	Therapeutics 10/2021 - 01/2014
3	Ligation 12/2021 - 01/2019
2	Surgical Instruments (Clip) 10/2023 - 10/2017
2	Punctures 12/2021 - 01/2019
2	Denervation 07/2020 - 01/2020